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Genetics and the Effect of Aging on Stem Cell Regulation
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Description: 1) To present an example of the use of mouse genetics to identify genes of importance in human disease. 2) To illustrate an example of basic research moving into the arena of translational research. 3) To highlight the importance of taking genetic diversity in human populations into account when planning treatment modalities. 4) To underscore that cancer cells are characterized by a variety of dysregulated genes that when properly regulated are important in normal cell function. "The most exciting thing to me about being a scientist is the anticipation of what discovery lies around the bend just ahead on the path. What is especially rewarding is when the discovery has the potential to advance the treatment of patients." Gary Van Zant
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