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Symptom Management and Quality-of-Life Improvement Following Transplantation / The Gender Biology of Pain
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Description:
Symptom Management and Quality-of-Life Improvement Following Transplantation
Transplantation: This 15-year program of research examines quality of life in transplant recipients following an intervention to reduce adverse events, enhance social support, and facilitate reemployment. Early treatment of infections reduced hospitalization for infections by 50 percent; participation in support group activities increased fivefold, and of the once-disabled patients, 86 percent of the intervention group, vs. 28 percent of controls, are employed. Use of this intervention through the standard nursing interventions in a team approach can positively influence quality-of-life outcomes.
The Gender Biology of Pain
In clinical pain management, choice of analgesic therapies is based primarily on the underlying disease, e.g., arthritis, diabetes. However, the patient's sex may be a critical additional factor for analgesic therapy success. Jon D. Levine found that sex influences the pharmacology of mechanisms that produce inflammation, sensitize pain-sensitive nerve fibers, and produce opiate analgesia. These effects, some mediated by sex hormones, can differ with age. Greater understanding of these factors may help optimize existing pain therapies and guide development of novel analgesic treatments.
Speaker(s):
Donna Hathaway, Ph.D., RN, FAAN, dean, professor of Nursing, professor of Transplant Surgery, University of Tennessee Health Science CenterJon D. Levine, M.D., Ph.D., professor of Dentistry, Medicine, Nursing, and Anatomy; director National Institutes of Health Pain Center, University of California San Francisco; member, graduate programs in neuroscience and biomedical sciences
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