Description:
The fruit fly’s internal clock mechanism, like the human mechanism, involves the complex interaction of many genes that produce the organism’s molecular clockworks. Dr. Michael Rosbash explains how fluctuating levels of specific cellular proteins operate in a negative-feedback loop to produce a molecular timekeeping mechanism. This “negative-feedback model” has proved applicable to clocks that are present in nearly every organism studied to date, from bacteria to mice and humans.
Speaker(s):
Michael Rosbash, Ph.D., HHMI investigator; professor of biology, Brandeis University; adjunct professor of molecular biology, Massachusetts General Hospital
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